Deanne was born in Los Angeles and spent most of her life growing up in southern California. She is profoundly deaf in her right ear and has an 86 decibel loss in her left ear. Deanne's husband, Troy Kotsur, is also a deaf actor. Deanne has appeared in Strong Medicine, CSI: Crime Scene Investigation, Rescue Me, Law & Order:Criminal Intent, Curb Your Enthusiasm, and The L Word. She also had a starring role as the main character on the television program Sue Thomas: F.B.Eye.
- Deanne knows American Sign Language.
- Deanne has received her B.A. in biology from California State University, Northridge.
- According to Heroes Interactive, Deanne taught math and science to deaf high school students before she became an actress.